Pyruvate Dehydrogenase Acetyl-Transferring Kinase

A pyruvate dehydrogenase kinase isozyme located in the mitochondria which converts PYRUVATE to ACETYL CoA in the CITRIC ACID CYCLE, phosphorylates SERINE residues on pyruvate dehydrogenase using ATP, and plays a key role in the regulation of GLUCOSE and fatty acid metabolism.

Also Known As:

Dehydrogenase Kinase, Pyruvate; Kinase, PDH; Kinase, Pyruvate Dehydrogenase; Pyruvate Dehydrogenase Acetyl Transferring Kinase; PDH Kinase; Pyruvate Dehydrogenase (Acetyl-Transferring) Kinase; Pyruvate Dehydrogenase (Lipoamide) Kinase; Pyruvate Dehydrogenase Kinase

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Transferases: 6719
    - Phosphotransferases: 43773
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9899
        Protein Serine-Threonine Kinases: 3707
        Pyruvate Dehydrogenase Acetyl-Transferring Kinase: 417
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Serine-Threonine Kinases: 3707
      - Pyruvate Dehydrogenase Acetyl-Transferring Kinase: 417

P V Blair Selected Research

P V Blair Research Topics

Disease

Drug/Important Bio-Agent (IBA)